Decades-old model of slow adaptation in sensory hair cells is not supported in mammals
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چکیده
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Sensory transduction and adaptation in inner and outer hair cells of the mouse auditory system.
Auditory function in the mammalian inner ear is optimized by collaboration of two classes of sensory cells known as inner and outer hair cells. Outer hair cells amplify and tune sound stimuli that are transduced and transmitted by inner hair cells. Although they subserve distinct functions, they share a number of common properties. Here we compare the properties of mechanotransduction and adapt...
متن کاملTransduction and adaptation in sensory hair cells of the mammalian vestibular system.
The human vestibular apparatus detects head movements and gravitational stimuli which impinge upon the mechanosensory hair cells of the inner ear. The hair cells, in turn, transduce these stimuli into electrical signals which are transmitted to the brain. These sensory cells are exquisitely responsive, signaling deflections of their mechanosensitive organelles as small as 1-2 nanometers. Remark...
متن کاملSyntaxin 1 is expressed in the trout saccular hair cells: RT-PCR and immunocytochemical observations
Syntaxin is one of several proteins that may be involved in the docking of synaptic vesicles, synaptic vesicle recycling, and non-synaptic membrane trafficking. Presence of syntaxin has been reported in rat auditory and vestibular end organs. In the current study, we have examined the expression of message for syntaxin 1 in hair cells of the sacculus of the rainbow trout, Oncorhynchus mykiss, w...
متن کاملSyntaxin 1 is expressed in the trout saccular hair cells: RT-PCR and immunocytochemical observations
Syntaxin is one of several proteins that may be involved in the docking of synaptic vesicles, synaptic vesicle recycling, and non-synaptic membrane trafficking. Presence of syntaxin has been reported in rat auditory and vestibular end organs. In the current study, we have examined the expression of message for syntaxin 1 in hair cells of the sacculus of the rainbow trout, Oncorhynchus mykiss, w...
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ژورنال
عنوان ژورنال: Science Advances
سال: 2020
ISSN: 2375-2548
DOI: 10.1126/sciadv.abb4922